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- Bioss
- bs-7619P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-7619P |
| 英文名称 | PSRC1 Antibody Blocking Peptide |
| 中文名称 | 富含脯氨酸/丝氨酸卷曲螺旋蛋白1封闭多肽 |
| 英文别名 | DDA3; Differential display and activated by p53; FP3214; p53-regulated DDA3; Proline/serine-rich coiled-coil 1; proline/serine-rich coiled-coil protein 1; PSRC1_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Cell cycle > Cell cycle inhibitors > p53 pathway Cell Biology > Apoptosis > Intracellular > p53 Pathway Cell Biology > Cell Cycle > Cell Cycle Inhibitors > p53 |
| 亚基 | Interacts with APC2 (By similarity). Interacts with KIF2A. |
| 亚细胞定位 | Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Detected at the mitotic spindle and spindle poles. Diffusely distributed throughout the cell during interphase. |
| 组织特异性 | Widely expressed in adult and fetal tissues, with highest expression in the adult brain and fetal thymus. Not detected in adult skeletal muscle. |
| 翻译后修饰 | Phosphorylated during mitosis. |
| 相似性 | Belongs to the PSRC1 family. |
| 功能 | Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase. Plays a role in the regulation of mitotic spindle dynamics. Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores. Recruits KIF2A to the mitotic spindle and spindle poles. May participate in p53/TP53-regulated growth suppression. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a proline rich protein. Studies of the related mouse gene suggest that this gene is regulated by p53 and may participate in p53 mediated growth suppression. Alternatively spliced transcript variants encoding different isoforms have been described. |
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PSRC1 Antibody Blocking Peptide(bs-7619P)-500ug
￥880
