- ￥880
- Bioss
- bs-9022P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-9022P |
| 英文名称 | IQCG Antibody Blocking Peptide |
| 中文名称 | IQCG蛋白封闭多肽 |
| 英文别名 | IQ domain containing protein G; IQ motif containing G; DKFZp434B227; FLJ11667; FLJ23571; FLJ37775; IQCG_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Other Antibodies > Other Antibodies |
| 相似性 | Contains 1 IQ domain. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | IQCG is a 443 amino acid protein containing one IQ domain. Widely distributed in nature, the IQ domain forms an amphiphilic seven-turn α-helix capable of binding calmodulin in a Ca2+-independent manner. The level of intracellular calcium is tightly regulated in all eukaryotic cells. A modest increase in this level can result in a myriad of physiological responses, most of which are mediated by calmodulin (CaM), the universal calcium sensor. In acute T-lymphoid/myeloid leukemia, IQCG forms a complex with Nup98, an O-linked glycoprotein and a component of the nuclear pore complex. NUP98-IQCG complex bind co-activators and/or co-repressors, which suggest a role in transcriptional regulation.Nup98-IQCG complex inhibits 32Dcl3 cell apoptosis induced by Arabinofuranosylcytosine (Ara-C) and partially blocks granulocyte differentiation induced by G-CSF. IQCG exists as two isoforms due to alternatively splicing events. |
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IQCG Antibody Blocking Peptide(bs-9022P)-500ug
￥880
