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- Bioss
- bs-20303P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-20303P |
| 英文名称 | HAP1 Antibody Blocking Peptide |
| 中文名称 | 舞蹈症相关蛋白1封闭多肽 |
| 英文别名 | Huntingtin Associated Protein 1; HAP 1; HAP 2; HAP-1; Hap1; HAP1_HUMAN; HAP2; HAPP; hHAP1; hHLP1; HIP 5; HIP5; HLP; HLP1; Huntingtin-associated protein 1; huntingtin-associated protein 2; Neuroan 1; Neuroan1. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurology process > Neurodegenerative disease > Huntington's disease Neuroscience > Neurology process > Neurogenesis Signal Transduction > Protein Trafficking > Vesicle Transport > Regulation |
| 组织特异性 | Predominantly expressed in brain. Selectively expressed in neurons. |
| 相似性 | Contains 1 HAP1 N-terminal domain. |
| 功能 | Associates specifically with huntingtin. This binding is enhanced by an expanded polyglutamine repeat. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
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HAP1 Antibody Blocking Peptide(bs-20303P)-500ug
￥880
