TNFRSF8 Antibody Blocking Peptide(bs-8769P)-500ug

TNFRSF8 Antibody Blocking Pept

ide(bs-8769P)-500ug
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  • bs-8769P
  • 2025年10月16日
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      500ug

    产品编号bs-8769P
    英文名称TNFRSF8 Antibody Blocking Peptide
    中文名称CD30封闭多肽
    英文别名CD 30; CD30; CD30 antigen; CD30L receptor; Cytokine receptor CD30; D1S166E; KI 1; Ki 1 antigen; Ki-1 antigen; KI1; Lymphocyte activation antigen CD30; TNFRSF 8; TNFRSF8; Tumor Necrosis Factor Receptor Superfamily Member 8; Tumor Necrosis Factor Receptor Superfamily Member 8; TNR8_HUMAN; Tumor necrosis factor receptor superfamily member 8; CD30L receptor; Ki-1 antigen; Lymphocyte activation antigen CD30; CD_antigen=CD30.
    纯化方法HPLC
    研究领域

    Cancer > Tumor biomarkers > Receptors

    Cancer > Tumor immunology > CD markers

    Immunology > Cell Type Markers > CD > Non-lineage

    Immunology > Innate Immunity > Cytokines > TNF Superfamily

    亚基Interacts with TRAF1, TRAF2, TRAF3 and TRAF5.
    亚细胞定位Isoform Long: Cell membrane; Single-pass type I membrane protein.
    Isoform Short: Cytoplasm.
    组织特异性Detected in thymus and in activated splenocytes.
    翻译后修饰Phosphorylated on serine and tyrosine residues.
    相似性Contains 6 TNFR-Cys repeats
    功能Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

     

     

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