BCL2L15 Antibody Blocking Peptide(bs-7582P)-500ug

BCL2L15 Antibody Blocking Pept

ide(bs-7582P)-500ug
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  • ¥880
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  • bs-7582P
  • 2025年10月16日
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      500ug

    产品编号bs-7582P
    英文名称BCL2L15 Antibody Blocking Peptide
    中文名称BCL2样15促凋亡蛋白封闭多肽
    英文别名B2L15_HUMAN; Bcl-2-like protein 15; Bcl2-L-15; BCL2-like 15; Bcl2l15; Bfk; C1orf178; FLJ22588; pro-apoptotic Bcl-2 protein.
    纯化方法HPLC
    研究领域

    Cell Biology > Apoptosis > Intracellular > Bcl2 Family

    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料BCL2L15 is a 163 amino acid protein and novel member of the Bcl-2 family that contains both BH2 and BH3 regions, but not BH1, BH4 or a C-terminal hydrophobic membrane anchor. Like Bcl-GL, Bfk does not bind to any Bcl-2 family members, even though its BH3 motif can mediate association with prosurvival proteins. Bfk localizes to cytoplasm, but unlike Bcl-GL, Bfk does not associate with organelles. Existing as four alternatively spliced isoforms, the pro-apoptotic isoforms of Bfk may help to protect against the development of human gastrointestinal malignancy. Bfk is found at low levels in stomach, ovary, bone marrow and spleen, but Bfk is highly expressed in mammary gland during pregnancy, suggesting that Bfk may play a role in mammary development. Bfk appears to be a cytosolic protein whose gene maps to chromosome 1p13.2. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome.

     

     

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