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CD239 Antibody Blocking Peptid

e(bs-7546P)-500ug
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  • ¥880
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  • bs-7546P
  • 2025年10月16日
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      500ug

    产品编号bs-7546P
    英文名称CD239 Antibody Blocking Peptide
    中文名称B细胞粘附分子CD239封闭多肽
    英文别名Antigen identified by monoclonal antibody F8; AU antibody Auberger B antigen; B CAM cell surface glycoprotein; B cell adhesion molecule; B-CAM cell surface glycoprotein; Basal cell adhesion molecule; Basal cell adhesion molecule Lu and Au blood groups; Basal cell adhesion molecule Lutheran blood group; Bcam; BCAM_HUMAN; CD239; CD239 antigen; F8/G253 antigen; Glycoprotein 95kDa; LU; Lutheran; Lutheran antigen; Lutheran blood group (Auberger b antigen included); Lutheran blood group Auberger b antigen included; Lutheran blood group glycoprotein; MSK19.
    纯化方法HPLC
    研究领域

    Cardiovascular > Atherosclerosis > Thrombosis

    Cardiovascular > Blood

    Cardiovascular > Blood > Blood Cell Antigens

    Immunology > Immunoglobulins > Receptors

    亚细胞定位Membrane; Single-pass type I membrane protein.
    组织特异性Wide tissue distribution (highest in the pancreas and very low in brain). Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel walls.
    翻译后修饰Epinephrine-stimulated phosphorylation of Ser-621 by PKA enhances adhesion to laminin.
    相似性Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 2 Ig-like V-type (immunoglobulin-like) domains.
    功能Laminin alpha-5 receptor. May mediate intracellular signaling.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].

     

     

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