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- bs-3933P
- 2025年10月16日
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500ug
| 产品编号 | bs-3933P |
| 英文名称 | Cacna1e Antibody Blocking Peptide |
| 中文名称 | L型钙通道蛋白a1亚型6封闭多肽 |
| 英文别名 | BII; Brain calcium channel II; CAC 1E; CAC1E; CACH 6; CACH6; CACNA1E; Cacnl1 a6; CACNL1A6; Calcium channel, L type, alpha 1 polypeptide, isoform 6; calcium channel, R type; Cav 2.3; Cchra 1; Cchra1; Voltage dependent R type calcium channel subunit alpha 1E; Voltage gated calcium channel subunit alpha Cav2.3. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Cancer Metabolism > Metabolic signaling pathway > Integration of energy metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Integration of energy Neuroscience > Neurotransmission > Calcium Signaling > Calcium Channels > P / Q / R -Type Signal Transduction > Signaling Pathway > Calcium Signaling > Calcium Channels |
| 亚细胞定位 | Membrane; Multi-pass membrane protein. |
| 组织特异性 | Expressed in neuronal tissues and in kidney. |
| 相似性 | Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1E subfamily. Contains 1 EF-hand domain. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Calcium channels mediate the influx of calcium ions into the cell following membrane polarisation. R-type calcium channels such as Cav2.3 belong to the "high voltage-activated" group and are blocked by nickel. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Each of these proteins exists as multiple isoforms, either encoded by different genes or arising from alternative splicing of transcripts. Cav2.3 is an alpha-1 subunit and has 24 transmembrane segments, which form the pore through which ions pass into the cell. Calcium channels containing the Cav2.3 subunit may be involved in the modulation of firing patterns of neurons, which is important for information processing. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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