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- Bioss
- bs-18592P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-18592P |
| 英文名称 | Lysosomal acid lipase Antibody Blocking Peptide |
| 中文名称 | 胆固醇酯水解酶封闭多肽 |
| 英文别名 | Acid Cholesteryl Ester Hydrolase; CESD; cholesterol ester hydrolase; cholesterol ester storage disease; Cholesteryl Esterase; Hydrolase deficiency; LAL; LAL deficiency cholesterol ester; LICH_HUMAN; LIPA; LIPA deficiency; Lipase A; lipase A, lysosomal acid, cholesterol esterase; lysosomal acid lipase; lysosomal acid lipase deficiency; Lysosomal acid lipase/cholesteryl ester hydrolase; Sterol esterase. |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Lipids / Lipoproteins > Lipid Metabolism > Lipases Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipases Metabolism > Types of disease > Cancer Signal Transduction > Metabolism > Lipid metabolism |
| 亚细胞定位 | Lysosome. |
| 相似性 | Belongs to the AB hydrolase superfamily. Lipase family. |
| 功能 | Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2014] |
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Lysosomal acid lipase Antibody Blocking Peptide(bs-18592P)-500ug
￥880
