RTL10 Antibody Blocking Peptide(bs-15135P)-500ug

RTL10 Antibody Blocking Peptid

e(bs-15135P)-500ug
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  • ¥880
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  • bs-15135P
  • 2025年10月16日
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      500ug

    产品编号bs-15135P
    英文名称RTL10 Antibody Blocking Peptide
    中文名称22号染色体开放阅读框29封闭多肽
    英文别名C22orf29; CV029_HUMAN; Uncharacterized protein C22orf29.
    纯化方法HPLC
    亚基Interacts (via BH3 domain) with VDAC1. Interacts withpro-survival Bcl-2 family members, BCL2, BCL2L1 isoform Bcl-X(L),MCL1, BCL2A1 and BCL2L2. Interacts with BAX and BAK.
    亚细胞定位Mitochondrion.
    组织特异性Ubiquitously expressed.
    功能Could induce apoptosis in a BH3 domain-dependent manner.The direct interaction network of Bcl-2 family members may play akey role in modulation BOP intrinsic apoptotic signaling activity.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Chromosome 22 contains over 500 genes and about 49 million bases. Being the second smallest human chromosome, 22 contains a surprising variety of interesting genes. Phelan-McDermid syndrome, neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translo-acations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein, Bcr-Abl, a potent cell proliferation activator found in several types of leukemia. The C22orf29 gene product has been provisionally designated C22orf29 pending further characterization

     

     

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