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- Bioss
- bs-23799P
- 2025年10月16日
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500ug
| 产品编号 | bs-23799P |
| 英文名称 | phospho-Gli1 (S112/ T115/ S116) Antibody Blocking Peptide |
| 中文名称 | 磷酸化脑胶质瘤相关蛋白封闭多肽 |
| 英文别名 | Phospho-Gli1 (Ser112/ Thr115/ Ser116); P-Gli1 (Ser112/ Thr115/ Ser116); Gli1 (Phospho-Ser112/ Thr115/ Ser116); Gli 1; Gli1; Gli-1; GLI; GLI Kruppel family member 1; Glioma associated oncogene; Glioma associated oncogene homolog 1 (zinc finger protein); Oncogene GLI; Zfp 5; Zfp5; Zinc finger protein GLI 1; Zinc finger protein GLI1; GLI1_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Oncoproteins/suppressors > Tumor suppressors > PTC & Wnt pathway Epigenetics and Nuclear Signaling > Transcription > Domain Families > Krueppel like factor Epigenetics and Nuclear Signaling > Transcription > Domain Families > Zinc Finger Neuroscience > Neurology process > Neural Signal Transduction Stem Cells > Signaling Pathways > Hedgehog > Nuclear |
| 亚细胞定位 | Cytoplasm. Nucleus. Tethered in the cytoplasm by binding to SUFU. Activation and translocation to the nucleus is promoted by interaction with STK36. Phosphorylation by ULK3 may promote nuclear localization. Translocation to the nucleus is promoted by interaction with ZIC1. |
| 组织特异性 | Testis, myometrium and fallopian tube. Also expressed in the brain with highest expression in the cerebellum, optic nerve and olfactory tract. |
| 功能 | Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] |
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phospho-Gli1 (S112/ T115/ S116) Antibody Blocking Peptide(bs-23799P)-500ug
￥1080
