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- Bioss
- bs-11181P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-11181P |
| 英文名称 | Neuroligin 3 Antibody Blocking Peptide |
| 中文名称 | 突触细胞粘附分子3封闭多肽 |
| 英文别名 | Gliotactin homolog; Neuroligin3; Neuroligin-3; Nlgn3; NLGN3_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Cell Type Marker > Glia marker > Astrocyte marker Neuroscience > Cell Type Marker > Glia marker > Oligodendrocyte marker Neuroscience > Neurology process > Neurogenesis |
| 亚基 | Interacts with NRXN1, NRXN2 and NRXN3. Interacts (via its C-terminus) with DLG4/PSD-95 (via PDZ domain 3). Homodimer, and heterodimer with NLGN1 and NLGN2. |
| 亚细胞定位 | Cell membrane; Single-pass type I membrane protein. Cell junction, synapse. Note=Detected at both glutamatergic and GABAergic synapses |
| 组织特异性 | Expressed in the blood vessel walls (at protein level). Detected in throughout the brain and in spinal cord. Detected in brain, and at lower levels in pancreas islet beta cells. |
| 相似性 | Belongs to the type-B carboxylesterase/lipase family. |
| 功能 | Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and may mediate its effects by clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Oct 2009]. |
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Neuroligin 3 Antibody Blocking Peptide(bs-11181P)-500ug
￥880
