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- Bioss
- bs-1169P
- 2025年10月16日
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500ug
| 产品编号 | bs-1169P |
| 英文名称 | CCR-1 Antibody Blocking Peptide |
| 中文名称 | 细胞表面趋化因子受体1封闭多肽 |
| 英文别名 | CC chemokine receptor 1; A630091E18Rik; CC-CKR-11; CCBP2; CCR10; CCR11; CCRL1; CCX-CKR; CCX-CKR1; CKR-11; Cmkbrl1; LOC684092; LOC685243; PPR1; VSHK1; C C chemokine receptor type 1; C C CKR 1; CC CKR 1; CCR 1; CD 191; CD191; CD191; Chemokine (C-C motif) receptor 1; Chemokine C C motif receptor 1; CKR 1; CKR1; CMKBR 1; CMKBR1; CMKR 1; CMKR1; HM145; LD78 receptor; Macrophage inflammatory protein 1 alpha /Rantes receptor; Macrophage inflammatory protein 1 alpha receptor; MIP 1alpha R; Mip-1a-R; MIP1aR; RANTES R; RANTES receptor; SCYAR1; CCR1_HUMAN; C-C chemokine receptor type 1; C-C CKR-1; CC-CKR-1; Short=CCR-1; CCR1; LD78 receptor; MIP-1alpha-R; RANTES-R; CD191. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Innate Immunity > Chemokines > Beta Chemokine Rec. (CCR) Microbiology > Organism > Virus > RNA Virus > ssRNA positive strand virus > SARS Coronavirus |
| 亚基 | Interacts with CREB3. |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 组织特异性 | Widely expressed in different hematopoietic cells. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. |
| 功能 | Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | bs-1169P is a synthetic peptide derived from human CCR-1. This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008] |
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CCR-1 Antibody Blocking Peptide(bs-1169P)-500ug
￥880
