- ￥880
- Bioss
- bs-23178P
- 2025年10月16日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-23178P |
| 英文名称 | MRC1 Antibody Blocking Peptide |
| 中文名称 | 巨噬细胞甘露糖受体 (CD206) 封闭多肽 |
| 英文别名 | Mannose Receptor; C-type lectin domain family 13 member D; CD 206; CD206; CD206 antigen; CLEC13D; CLEC13DL; Macrophage mannose receptor; Mannose receptor C type 1; MMR; MRC 1; MRC-1; MRC1_HUMAN; MRC1; MRC1L1; C-type lectin domain family 13 member D-like; Macrophage mannose receptor 1-like protein 1. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Immunoglobulins > Receptors Immunology > Innate Immunity > Macrophage / Inflamm. |
| 亚细胞定位 | Endosome membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein. |
| 相似性 | Contains 8 C-type lectin domains.
Contains 1 fibronectin type-II domain. [SIMILARITY] Contains 1 ricin B-type lectin domain. |
| 功能 | Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. This gene is in close proximity to MRC1L1. The gene loci including this gene, MRC1L1, as well as LOC340843 and LOC340893, consist of two nearly identical, tandemly linked genomic regions, which are thought to be a part of a duplicated region. [provided by RefSeq]. |
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MRC1 Antibody Blocking Peptide(bs-23178P)-500ug
￥880
