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- 规格:
500ug
| 产品编号 | bs-2639P |
| 英文名称 | PTGES2 Antibody Blocking Peptide |
| 中文名称 | 前列腺素E合成酶2封闭多肽 |
| 英文别名 | C9orf15; FLJ14038; Gamma interferon activated transcriptional element binding factor 1; GATE binding factor 1; GBF 1; GBF1; Membrane associated prostaglandin E synthase 2; MGC11289; Microsomal prostaglandin E synthase 2; mPGES 2; mPGES-2; PGES2; PGES2_HUMAN; Prostaglandin E synthase 2; Prostaglandin E synthase 2 truncated form; PTGES 2; PGES2_MOUSE. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 亚基 | Homodimer. May interact with CEBPB. |
| 亚细胞定位 | Golgi apparatus membrane; Single-pass membrane protein. Nucleus. Note=According to PubMed:12050152, some fraction may be nuclear. Prostaglandin E synthase 2 truncated form: Cytoplasm. Note=Synthetized as a Golgi membrane-bound protein, which is further cleaved into the predominant soluble truncated form. |
| 组织特异性 | Widely expressed. Expressed in brain, heart, liver, colon and lung. |
| 相似性 | Belongs to the GST superfamily.
Contains 1 glutaredoxin domain. Contains 1 GST C-terminal domain. |
| 功能 | Isomerase that catalyzes the conversion of unstable intermediate of prostaglandin E2 H2 (PGH2) into the more stable prostaglandin E2 (PGE2) form (By similarity). May also have transactivation activity toward IFN-gamma (IFNG), possibly via an interaction with CEBPB; however, the relevance of transcription activation activity remains unclear. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene. [provided by RefSeq]. |
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PTGES2 Antibody Blocking Peptide(bs-2639P)-500ug
¥800





