- ￥880
- Bioss
- bs-17618P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-17618P |
| 英文名称 | SPAG11B Antibody Blocking Peptide |
| 中文名称 | 精子相关抗原11B封闭多肽 |
| 英文别名 | EP2; EP2C; EP2D; Epididymal protein 2; HE2; HE2C; Protein EP2; SPAG11; Sperm antigen HE2; Sperm associated antigen 11; Sperm associated antigen 11B. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Secreted |
| 组织特异性 | Specifically expressed in caput and proximal corpus of epididymis. Present in the epididymal epithelium and on the sperm surface, with a subacrosomal equatorial distribution on the sperm head. |
| 相似性 | Belongs to the SPAG11 family. |
| 功能 | SPAG11B belongs to the SPAG11 family. The specific function of SPAG11B has not been determined, but it is thought to be involved in sperm maturation. It is specifically expressed in caput and proximal corpus of epididymis and is present in the epididymal epithelium and on the sperm surface, with a subacrosomal equatorial distribution on the sperm head. There are two named isoforms. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | SPAG11B is a 103 amino acid precursor protein that exists as four alternatively spliced isoforms, designated EP2A, EP2B, EP2C and EP2D, all of which are androgen-dependent, epididymis-specific secretory proteins that may play a role in sperm maturation and overall function. The gene encoding the SPAG11B precursor maps to a region on chromosome 8 that is near the ∫-defensin gene cluster and it is suggested that SPAG11B may exhibit functional characteristics (such as antimicrobial activity) that are similar to ∫-defensins. Human chromosome 8, on which the SPAG11B gene is localized, consists of nearly 146 million base pairs and houses more than 800 genes, some of which are associated with a variety of diseases and malignancies. |
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SPAG11B Antibody Blocking Peptide(bs-17618P)-500ug
￥880
