CHCHD7 Antibody Blocking Peptide(bs-13889P)-500ug

CHCHD7 Antibody Blocking Pepti

de(bs-13889P)-500ug
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  • ¥880
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  • bs-13889P
  • 2025年10月16日
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      500ug

    产品编号bs-13889P
    英文名称CHCHD7 Antibody Blocking Peptide
    中文名称卷曲螺旋结构域蛋白CHCHD7封闭多肽
    英文别名Coiled coil helix coiled coil helix domain containing 7; Coiled coil helix coiled coil helix domain containing protein 7; COX23; CHCH7_HUMAN; COX23 cytochrome c oxidase assembly homolog.
    纯化方法HPLC
    亚基Monomer.
    亚细胞定位Mitochondrion intermembrane space
    相似性Belongs to the CHCHD7 family.
    Contains 1 CHCH domain.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料CHCHD7 is an 85 amino acid protein that contains one CHCH domain. A chromosomal translocation involving the CHCHD7 gene and PLAG1 gene is found in salivary gland pleiomorphic adenomas, the most common benign epithelial tumors of the salivary gland. There are three isoforms of CHCHD7 that are produced as a result of alternative splicing events. The gene encoding CHCHD7 maps to human chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects.

     

     

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