- ￥880
- Bioss
- bs-23726P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-23726P |
| 英文名称 | SBNO2 Antibody Blocking Peptide |
| 中文名称 | SBNO2蛋白封闭多肽 |
| 英文别名 | FLJ00173; KIAA0963; Protein strawberry notch homolog 2; SBNO2; Sno; Stno. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Transcription Factors Immunology > Innate Immunity > Macrophage / Inflamm. |
| 功能 | SBNO2 appears to have transcriptional repression activity in macrophages. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | SBNO2 is a 1,366 amino acid protein that belongs to the SBNO family. Detected in macrophages, SBNO2 seems to have transcriptional repression activity. SBNO2 and ETV3 are components of the pathways that contribute to the downstream anti-inflammatory effects of IL-10. The expression of SBNO2 is regulated by IL-10 in a STAT3-dependent way. Existing as two alternatively spliced isoforms, the SBNO2 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish and C.elegans, and maps to human chromosome 19p13.3. GPx-4 and LKB1 are neiGHBors of SBNO2 on chromosome 19. Chromosome 19 consists of approximately 63 million bases and makes up over 2% of human genomic DNA. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. |
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SBNO2 Antibody Blocking Peptide(bs-23726P)-500ug
￥880
