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500ug
| 产品编号 | bs-11174P |
| 英文名称 | KY/Kyphoscoliosis peptidase Antibody Blocking Peptide |
| 中文名称 | 脊柱侧后凸畸形肽酶封闭多肽 |
| 英文别名 | KY; KY_HUMAN; Kyphoscoliosis peptidase. |
| 纯化方法 | HPLC |
| 研究领域 | Developmental Biology > Organogenesis > Skeletal development > Muscle Neuroscience > Cell Adhesion Proteins > Proteases |
| 亚基 | Interacts with IGFN1 and FLNC. |
| 亚细胞定位 | Cytoplasm |
| 组织特异性 | Specifically expressed in skeletal and cardiac muscle. |
| 相似性 | Belongs to the transglutaminase-like superfamily. |
| 功能 | Probable cytoskeleton-associated protease required for normal muscle growth. Involved in function, maturation and stabilization of the neuromuscular junction. May act by cleaving muscle-specific proteins such as FLNC. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | KY peptidase (Kyphoscoliosis peptidase) is a 561 amino acid cytoskeleton protease that interacts with several sarcomeric cytoskeletal proteins, including Filamin 2. KY peptidase probably plays a role in the maturation, function and stabilization of the neuromuscular junction. KY-null mouse mutants exhibit distinct irregular subceullular Filamin 2 localization, suggesting that KY peptidase deficiency may be the cause of several types of limb-girdle muscular dystrophies. |
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KY/Kyphoscoliosis peptidase Antibody Blocking Peptide(bs-11174P)-500ug
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