PCDHGB2 Antibody Blocking Peptide(bs-11156P)-500ug产品图

PCDHGB2 Antibody Blocking Pept

ide(bs-11156P)-500ug
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  • ¥880
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  • bs-11156P
  • 2025年10月16日
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      500ug

    产品编号bs-11156P
    英文名称PCDHGB2 Antibody Blocking Peptide
    中文名称原钙粘蛋白γB2封闭多肽
    英文别名PCDH-gamma-B2; Protocadherin gamma B2; PCDGE_HUMAN.
    纯化方法HPLC
    亚细胞定位Cell Membrane
    相似性Contains 6 cadherin domains.
    功能Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. The protocadherein gamma cluster consists of three subfamilies (A, B and C). As a member of the gamma subfamily B, PCDHGB2 (Protocadherin gamma B2) is a 931 amino acid protein that is one of 22 proteins encoded by the protocadherin gamma cluster. Typical of gamma protocadherins, PCDHGB2 contains six cadherin motifs and is a type I transmembrane receptor expressed in the central nervous system. With localization to synapses, members of the gamma cluster of protocadherins are essential for neuronal survival. There are two isoforms of PCDHGB2 that are produced as a result of alternative splicing events.

     

     

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