- ￥880
- Bioss
- bs-7672P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-7672P |
| 英文名称 | NRH2 Antibody Blocking Peptide |
| 中文名称 | 死亡结构域蛋白NRH2封闭多肽 |
| 英文别名 | NRADD; PLAIDD; NRADD_RAT; Death domain-containing membrane protein NRADD; Neurotrophin receptor homolog-2; Neurotrophin receptor-alike death domain protein; P75-like apoptosis-inducing death domain protein. |
| 纯化方法 | HPLC |
| 亚基 | Interacts with NTRK1. Isoform 1 andisoform 2 interact with NGFR. Interacts with SORT1. |
| 亚细胞定位 | Cell membrane; Single-pass type III membraneprotein. Nucleus (By similarity). Note=Proteolytic processing givesrise to an intracellular domain that translocates to the nucleus. |
| 组织特异性 | Detected in embryo, including embryonic brain.Detected at very low levels in adult testis, spleen, thymus andlung. |
| 翻译后修饰 | Isoform 1 is N-glycosylated. Isoform 2 is not N-glycosylated. |
| 相似性 | Contains 1 death domain. |
| 功能 | Modulates NTRK1 signaling. Can activate severalintracellular signaling pathways, leading to activation of JUN.Promotes translocation of SORT1 to the cell membrane, and therebyhinders lysosomal degradation of SOTR1 and promotes its interactionwith NGFR (By similarity). Both isoform 1 and isoform 2 promoteapoptosis. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | A single transmembrane protein highly expressed in embryonic tissues and involved in inducing apoptosis. |
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NRH2 Antibody Blocking Peptide(bs-7672P)-500ug
￥880
