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- bs-23677P
- 2025年10月16日
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500ug
| 产品编号 | bs-23677P |
| 英文名称 | Ctip2 Antibody Blocking Peptide |
| 中文名称 | B淋巴细胞白血病/淋巴瘤11B封闭多肽 |
| 英文别名 | B cell lymphoma/leukemia 11B; B-cell CLL/Lymphoma 11B; B-cell lymphoma/leukemia 11B; BC11B_HUMAN; BCL-11B; Bcl11B; COUP-TF interacting protein 2; COUP-TF-interacting protein 2; Ctip 2; hRit1; MS1029; Radiation induced tumor suppressor gene 1; Radiation induced tumor suppressor gene 1 protein; Radiation-induced tumor suppressor gene 1 protein; Rit 1; Rit1. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Chromatin Modifying Enzymes > Acetylation Epigenetics and Nuclear Signaling > Chromatin Modifying Enzymes > Acetylation > HAT Epigenetics and Nuclear Signaling > Transcription > Domain Families > Zinc Finger Epigenetics and Nuclear Signaling > Transcription > Transcription Factors Neuroscience > Neurology process > Neural Signal Transduction Neuroscience > Neurology process > Neurogenesis |
| 亚基 | Interacts with TFCOUP1, SIRT1, ARP1 and EAR2 |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Highly expressed in brain and in malignant T-cell lines derived from patients with adult T-cell leukemia/lymphoma. |
| 相似性 | Contains 6 C2H2-type zinc fingers. |
| 功能 | Tumor-suppressor protein involved in T-cell lymphomas. May function on the P53-signaling pathway. May be a key regulator of both differentiation and survival during thymocyte development. Repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2013] |
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Ctip2 Antibody Blocking Peptide(bs-23677P)-500ug
￥880
