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500ug
| 产品编号 | bs-16577P |
| 英文名称 | EMC6 Antibody Blocking Peptide |
| 中文名称 | 跨膜蛋白93封闭多肽 |
| 英文别名 | Transmembrane protein 93; 0610009E20Rik; 0610025L18Rik; MGC2963; OTTMUSP00000006414; OTTMUSP00000006415; RGD1309231; RP23-263M10.8; EMC6_HUMAN; TMEM93; Transmembrane protein 93. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Other Antibodies > Other Antibodies |
| 亚细胞定位 | Membrane; Multi-pass membrane protein |
| 相似性 | Belongs to the EMC6 family. |
| 功能 | TMEM93 belongs to the TMEM93 family. It is a multi-pass membrane protein. The function of the TMEM93 protein remains unknown. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | TMEM93 is a 110 amino acid protein encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dubé syndrome and Canavan disease are also associated with chromosome 17. |
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EMC6 Antibody Blocking Peptide(bs-16577P)-500ug
¥880







