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- bs-16580P
- 2025年10月16日
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- 详细信息
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- 规格：
500ug
| 产品编号 | bs-16580P |
| 英文名称 | MED24 Antibody Blocking Peptide |
| 中文名称 | TRAP100蛋白封闭多肽 |
| 英文别名 | Activator recruited cofactor 100 kDa component; ARC100; Cofactor required for Sp1 transcriptional activation subunit 4; CRSP complex subunit 4; CRSP100; CRSP4; DRIP100; hTRAP100; KIAA0130; MED24_HUMAN; MED 24; MED24; Mediator complex subunit 24; Mediator of RNA polymerase II transcription subunit 24; Mediator of RNA polymerase II transcription subunit 24 homolog; MGC8748; OTTHUMP00000164458; OTTHUMP00000164460; THRAP4; Thyroid hormone receptor associated protein 4; Thyroid hormone receptor associated protein complex 100 kDa component; Trapp100; Vitamin D3 receptor interacting protein complex component DRIP100. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > Nuclear Receptors > Co-activators/co-repressors Epigenetics and Nuclear Signaling > Transcription > Co-factors Epigenetics and Nuclear Signaling > Transcription > Mediator Complex Epigenetics and Nuclear Signaling > Transcription > Other factors |
| 亚基 | Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP. Interacts with AR. |
| 亚细胞定位 | Nuclear |
| 组织特异性 | Ubiquitous. Abundant in skeletal muscle, heart and placenta. |
| 相似性 | Belongs to the Mediator complex subunit 24 family. |
| 功能 | TRAP100 plays a role in transcriptional coactivation. It plays a role in nuclear hormone receptor mediated transactivation. TRAP100 is a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre initiation complex. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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MED24 Antibody Blocking Peptide(bs-16580P)-500ug
￥880
