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500ug
| 产品编号 | bs-10550P |
| 英文名称 | SLC29A2 Antibody Blocking Peptide |
| 中文名称 | 核苷转运蛋白ENT2封闭多肽 |
| 英文别名 | DER12; Equilibrative NBMPR-insensitive nucleoside transporter; Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter; Equilibrative nucleoside transporter 2; HNP36; Hydrophobic nucleolar protein, 36 kDa; SLC29A2; solute carrier family 29 (nucleoside transporters), member 29; Solute carrier family 29 member 2; S29A2_HUMAN. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Protein Trafficking > Nuclear Import / Export |
| 亚细胞定位 | Basolateral cell membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein. Note=Localized at the basolateral cell membrane in polarized MDCK cells. |
| 组织特异性 | Expressed in skeletal muscle, liver, lung, placenta, brain, heart, kidney and ovarian tissues. |
| 相似性 | Belongs to the SLC29A/ENT transporter (TC 2.A.57) family. |
| 功能 | ENT2 mediates equilibrative transport of purine, pyrimidine nucleosides and the purine base hypoxanthine. It is less sensitive than ENT1 to inhibition by nitrobenzylthioinosine (NBMPR), dipyridamole, dilazep and draflazine. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The uptake of nucleosides by transporters, such as SLC29A2, is essential for nucleotide synthesis by salvage pathways in cells that lack de novo biosynthetic pathways. Nucleoside transport also plays a key role in the regulation of many physiologic processes through its effect on adenosine concentration at the cell surface (Griffiths et al., 1997 [PubMed 9396714]).[supplied by OMIM, Nov 2008] |
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SLC29A2 Antibody Blocking Peptide(bs-10550P)-500ug
¥800







