SLC29A2 Antibody Blocking Peptide(bs-10550P)-500ug

SLC29A2 Antibody Blocking Pept

ide(bs-10550P)-500ug
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  • bs-10550P
  • 2025年10月16日
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      500ug

    产品编号bs-10550P
    英文名称SLC29A2 Antibody Blocking Peptide
    中文名称核苷转运蛋白ENT2封闭多肽
    英文别名DER12; Equilibrative NBMPR-insensitive nucleoside transporter; Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter; Equilibrative nucleoside transporter 2; HNP36; Hydrophobic nucleolar protein, 36 kDa; SLC29A2; solute carrier family 29 (nucleoside transporters), member 29; Solute carrier family 29 member 2; S29A2_HUMAN.
    性状Lyophilized
    纯化方法HPLC
    研究领域

    Signal Transduction > Protein Trafficking > Nuclear Import / Export

    亚细胞定位Basolateral cell membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein. Note=Localized at the basolateral cell membrane in polarized MDCK cells.
    组织特异性Expressed in skeletal muscle, liver, lung, placenta, brain, heart, kidney and ovarian tissues.
    相似性Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
    功能ENT2 mediates equilibrative transport of purine, pyrimidine nucleosides and the purine base hypoxanthine. It is less sensitive than ENT1 to inhibition by nitrobenzylthioinosine (NBMPR), dipyridamole, dilazep and draflazine.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The uptake of nucleosides by transporters, such as SLC29A2, is essential for nucleotide synthesis by salvage pathways in cells that lack de novo biosynthetic pathways. Nucleoside transport also plays a key role in the regulation of many physiologic processes through its effect on adenosine concentration at the cell surface (Griffiths et al., 1997 [PubMed 9396714]).[supplied by OMIM, Nov 2008]

     

     

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