delta Sarcoglycan Antibody Blocking Peptide(bs-14264P)-500ug

delta Sarcoglycan Antibody Blo

cking Peptide(bs-14264P)-500ug
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  • bs-14264P
  • 2025年10月16日
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      500ug

    产品编号bs-14264P
    英文名称delta Sarcoglycan Antibody Blocking Peptide
    中文名称肌营养蛋白δ/δ-sarcoglycan封闭多肽
    英文别名35 kDa dystrophin associated glycoprotein; 35 kDa dystrophin-associated glycoprotein; 35DAG; CMD1L; DAGD; Delta-sarcoglycan; Delta-SG; Dystrophin associated glycoprotein delta sarcoglycan; LGMD2F; MGC22567; Placental delta sarcoglycan; Sarcoglycan delta (35 kDa dystrophin associated glycoprotein); SG delta; SGCD; SGCD_HUMAN; SGCDP; SGD.
    纯化方法HPLC
    研究领域

    Developmental Biology > Organogenesis > Skeletal development > Muscle

    Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Proteins > Other ECM Proteins

    亚细胞定位Cell membrane > sarcolemma. Cytoplasm > cytoskelet
    组织特异性Most strongly expressed in skeletal and cardiac muscle. Also detected in smooth muscle. Weak expression in brain and lung.
    翻译后修饰Glycosylated.
    Disulfide bonds are present.
    相似性Belongs to the sarcoglycan beta/delta/gamma/zeta family.
    功能Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008]

     

     

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