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500ug
| 产品编号 | bs-24130P |
| 英文名称 | SLC5A11 Antibody Blocking Peptide |
| 中文名称 | 碳酸氢钠协同转运蛋白4-A11封闭多肽 |
| 英文别名 | homolog of rabbit KST1; KST1; Na(+)/myo-inositol cotransporter 2; na+/myo-inositol cotransporter 2; putative sodium-coupled cotransporter RKST1; RKST1; SC5AB_MOUSE; SGLT6; SLC5A11; SMIT2; sodium-dependent glucose cotransporter; sodium/glucose cotransporter KST1; sodium/myo-inositol cotransporter 2; Sodium/myo-inositol transporter 2; solute carrier family 5 (sodium/glucose cotransporter), member 11; solute carrier family 5 member 11. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Membrane. |
| 组织特异性 | Highest expression in heart, skeletal muscle, kidney, liver and placenta. Weaker expression in brain, colon, spleen, lung and peripheral blood leukocytes. |
| 相似性 | Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. |
| 功能 | Involved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D-chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D-xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Cotransporters, such as SLC5A11, represent a major class of proteins that make use of ion gradients to drive active transport for the cellular accumulation of nutrients, neurotransmitters, osmolytes, and ions Roll et al. (2002) [PubMed 12039040].[supplied by OMIM, Mar 2008] |
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SLC5A11 Antibody Blocking Peptide(bs-24130P)-500ug
¥880







