PCDHB6 Antibody Blocking Peptide(bs-13726P)-500ug

PCDHB6 Antibody Blocking Pepti

de(bs-13726P)-500ug
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  • ¥880
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  • bs-13726P
  • 2025年10月16日
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      500ug

    产品编号bs-13726P
    英文名称PCDHB6 Antibody Blocking Peptide
    中文名称原钙粘附蛋白β6封闭多肽
    英文别名PCDH beta6; PCDH beta 6; PCDHB 6; Protocadherin beta 6; PCDB6_HUMAN.
    纯化方法HPLC
    亚细胞定位Cell membrane. Single-pass type I membrane protein.
    相似性Contains 6 cadherin domains.
    功能PCDHB6 (Protocadherin beta 6) is a member of the protocadherin family, a subgroup of the cadherin superfamily. Protocadherins are neural cadherin-like cell adhesion proteins that are integral membrane proteins. The specific function of PCDHB6 is unknown but it is thought to be involved in the establishment and maintenance of specific neuronal connections in the brain. PCDHB6 is a member of the beta cluster of protocadherin genes on 5q31.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB6 (Protocadherin beta-6) is a 794 amino acid single pass transmembrane protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB6) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. PCDHB6 is likely a calcium-dependent cell adhesion protein that is involved in the maintenance of neural connections in the brain. Unlike most protocadherin-beta proteins, PCDHB6 has not one but two PXXP motifs within its cytoplasmic domain, suggesting a role in signal transduction cascade events.

     

     

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