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- 技术资料
- 规格:
500ug
| 产品编号 | bs-15537P |
| 英文名称 | ICT1 Antibody Blocking Peptide |
| 中文名称 | 肽酰tRNA水解酶ICT1封闭多肽 |
| 英文别名 | Digestion substraction 1; DS-1; DS1; Ict1; ICT1_HUMAN; Immature colon carcinoma transcript 1 protein; Immature colon carcinoma transcript 1 protein; mitochondrial; Peptidyl-tRNA hydrolase ICT1, mitochondrial; Peptidyl-tRNA hydrolase ICT1. |
| 纯化方法 | HPLC |
| 亚基 | Component of the mitochondrial 39S ribosomal subunit. |
| 亚细胞定位 | Mitochondrion. |
| 组织特异性 | Down-regulated during the in vitro differentiation of HT29-D4 colon carcinoma cells. |
| 相似性 | Belongs to the prokaryotic/mitochondrial release factor family. ICT1 subfamily. |
| 功能 | Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | ICT1 is a member of the prokaryotic/mitochondrial release factor family whose expression is downregulated over 4 fold upon colon stem cell differentiation. This downregulation of ICT1 could lead to its use as a marker for detection of colon carcinomas. |
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ICT1 Antibody Blocking Peptide(bs-15537P)-500ug
¥880







