PCDH10 Antibody Blocking Peptide(bs-13723P)-500ug

PCDH10 Antibody Blocking Pepti

de(bs-13723P)-500ug
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  • ¥880
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  • bs-13723P
  • 2025年10月16日
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    • 规格

      500ug

    产品编号bs-13723P
    英文名称PCDH10 Antibody Blocking Peptide
    中文名称原钙粘附蛋白10封闭多肽
    英文别名DKFZp761O2023; KIAA1400; MGC133344; OL PCDH; Ortholog of OL pcdh; OTTHUMP00000220001; PCD10_HUMAN; PCDH10; PCDH19; Protocadherin 10; Protocadherin-10.
    纯化方法HPLC
    研究领域

    Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Cadherins

    亚细胞定位Cell membrane.
    组织特异性Moderately expressed in all regions of the brain examined, as well as in testis and ovary, and low expression in all other tissues tested.
    相似性Contains 6 cadherin domains.
    功能Potential calcium-dependent cell-adhesion protein.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDH10 (protocadherin 10), also known as PCDH19 or OL-PCDH, is a 1,040 amino acid single-pass type I membrane protein that contains six cadherin domains and one transmembrane domain. Expressed at moderate levels in brain, ovary and testis and present at lower levels in all other tissues, PCDH10 functions as a calcium-dependent cell-adhesion protein that may function as a tumor suppressor. When underexpressed, PCDH10 is associated with the progression of various carcinomas, including gastric cancer.

     

     

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