PPAR-delta Antibody Blocking Peptide(bs-0250P)-500ug

PPAR-delta Antibody Blocking P

eptide(bs-0250P)-500ug
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  • ¥880
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  • bs-0250P
  • 2025年10月16日
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      500ug

    产品编号bs-0250P
    英文名称PPAR-delta Antibody Blocking Peptide
    中文名称D型-过氧化酶活化增生受体封闭多肽
    英文别名PPAR delta+beta; FAAR; MGC3931; NR1C2; NUC1; NUCI; NUCII; Nuclear hormone receptor 1; Nuclear receptor subfamily 1 group C member 2; Peroxisome proliferative activated receptor delta; Peroxisome proliferator-activated receptor beta (PPAR-beta); Peroxisome proliferator-activated receptor beta; Peroxisome proliferator-activated receptor delta; PPAR beta; PPAR-beta; PPAR-delta; PPAR-? PPARB; PPARD; PPARD_HUMAN.
    性状Lyophilized
    纯化方法HPLC
    研究领域

    Cardiovascular > Heart > Cardiac metabolism

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > Zinc Finger

    Kits/ Lysates/ Other > Kits > Cell Metabolism Kits > Lipid Metabolism Kits > Fatty acids

    Metabolism > Types of disease > Obesity

    亚细胞定位Nucleus.
    组织特异性Ubiquitous with maximal levels in placenta and skeletal muscle.
    相似性Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
    功能Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Heterodimer with the retinoid X receptor. Subcellular located at nuclear Tissue specificity: Heart, adrenal and intestine. Belongs to the nuclear hormone receptor family. NR1 subfamily. It Contains 1 nuclear receptor DNA-binding domain.

     

     

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