ZNHIT2 Antibody Blocking Peptide(bs-16415P)-500ug

ZNHIT2 Antibody Blocking Pepti

de(bs-16415P)-500ug
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  • ¥880
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  • bs-16415P
  • 2025年10月16日
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      500ug

    产品编号bs-16415P
    英文名称ZNHIT2 Antibody Blocking Peptide
    中文名称ZNHIT2蛋白封闭多肽
    英文别名C11orf5; FON; MGC120285; MGC120286; OTTHUMP00000230419; Protein FON; Zinc finger HIT domain-containing protein 2; Zinc finger HIT type containing 2; zinc finger, HIT domain containing 2; zinc finger, HIT type 2; ZNHI2_HUMAN; ZNHIT2.
    纯化方法HPLC
    研究领域

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > Zinc Finger

    Epigenetics and Nuclear Signaling > Transcription > Other factors

    组织特异性Low expression in most tissues; highly expressed in testis.
    相似性Contains 1 HIT-type zinc finger.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料ZNHIT2 (zinc finger, HIT-type containing 2), also known as FON, is a 403 amino acid protein that is highly expressed in the seminiferous tubules of testis, with low expression in other tissues. Containing one HIT-type zinc finger, ZNHIT2 is encoded by a gene that maps to human chromosome 11, which comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes.

     

     

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