- ￥880
- Bioss
- bs-1138P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-1138P |
| 英文名称 | SSTR2 Antibody Blocking Peptide |
| 中文名称 | 生长抑素受体2封闭多肽 |
| 英文别名 | somatostatin receptor 2; Somatostatin receptor type 2; SRIF1; SS2R; SST2; SSTR2; SRIF-1; SS-2-R; SS2-R; SSR2_HUMAN. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Cancer Metabolism > Metabolic signaling pathway > Hormone biosynthesis Metabolism > Pathways and Processes > Endocrine metabolism > Hormone biosynthesis Neuroscience > Neurology process > Neuroendocrinology > GH Regulation Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR Neuroscience > Neurotransmitter > Neuropeptides > Hormones |
| 亚基 | The C-terminus interacts with SHANK1 PDZ domain. |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 组织特异性 | Cerebrum and kidney. In lesser amounts in jejunum, colon and liver. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. |
| 功能 | Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Somatostatin is a tetradecapeptide that is widely distributed in the body and is one of five receptor subtypes termed SSTr1-. These receptors function in the regulation of numerous phsiological processes such as the secretion of insulin, glucagon and growth hormone as wel as cell growth induced by neuronal excitation in both the central and peripheral nervous systems. Somatostatin receptos are activated via sonatostatin secreted by nerve and endocrine cells. Somatostatin Receptor 2 (SSR2), along with SSR1, is expressed at the highest levels in the stomach and jejunum, cerebrum and kidney, respectively. |
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SSTR2 Antibody Blocking Peptide(bs-1138P)-500ug
￥880
