P2RX1 Antibody Blocking Peptide(bs-21358P)-500ug

P2RX1 Antibody Blocking Peptid

e(bs-21358P)-500ug
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  • bs-21358P
  • 2025年10月16日
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      500ug

    产品编号bs-21358P
    英文名称P2RX1 Antibody Blocking Peptide
    中文名称三磷酸腺苷受体受体P2X1封闭多肽
    英文别名 P2X1; ATP receptor; ATP receptor; H sapiens mRNA for ATP receptor; H.sapiens mRNA for ATP receptor; P2 RX1; P2RX1; P2RX1 protein; P2RX1_HUMAN; P2X purinoceptor 1; P2X receptor subunit 1; P2X1; P2X1 receptor; Purinergic receptor; Purinergic receptor P2X ligand gated ion channel 1; Purinergic receptor P2X ligand-gated ion channel 1; Purinergic receptor P2X1.
    纯化方法HPLC
    研究领域

    Cardiovascular > Vasculature > Vasoconstriction

    Cardiovascular > Vasculature > Vasodilation

    Neuroscience > Neurotransmission > Receptors / Channels > Ligand-Gated Ion Channels > P2X Receptors

    亚基Homo- or heteropolymers (By similarity).
    亚细胞定位Membrane; Multi-pass membrane protein.
    相似性Belongs to the P2X receptor family.
    功能Ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Seems to be linked to apoptosis, by increasing the intracellular concentration of calcium in the presence of ATP, leading to programmed cell death.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both. They are characterized by intracellular amino- and carboxy-termini. P2X receptors are expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, which acts as a neurotransmitter. The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP.

     

     

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