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- Bioss
- bs-11137P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-11137P |
| 英文名称 | IFNLR1 Antibody Blocking Peptide |
| 中文名称 | 白细胞介素28受体封闭多肽 |
| 英文别名 | Alternative namesIFNLR; Class II cytokine receptor CRF2/12; CRF2/12; Cytokine receptor family 2 member 12; IFN lambda R1; IFNLR1; il-28r1; IL28R alpha; Interferon lambda receptor 1; Interferon lambda receptor; Interleukin 28 receptor alpha chain; LICR2; Likely interleukin or cytokine receptor 2.I28RA_HUMAN |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Cell Type Markers > CD > Cytokines Immunology > Innate Immunity > Cytokines > Interleukins |
| 亚基 | Heterodimer with IL10RB. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein |
| 组织特异性 | Widely expressed. |
| 相似性 | Belongs to the type II cytokine receptor family.
Contains 1 fibronectin type-III domain. |
| 功能 | IL28RA is a class II cytokine receptor that interacts with IL10RB to bind IL28A, IL28B, and IL29, which are related to type I interferons. These ligands play a critical role in response to microbial challenge and activate the JAK/STAT signaling system. It heterodimers with IL10RB. There are 4 isoforms as result of alternative splicing. It is widely expressed. IL28RA belongs to the type II cytokine receptor family, and contains 1 fibronectin type III domain. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
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IFNLR1 Antibody Blocking Peptide(bs-11137P)-500ug
￥880
