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- bs-0437P
- 2025年10月16日
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1mg/5mg/10mg
| 规格： | 1mg | 产品价格： | ￥200.0 |
|---|---|---|---|
| 规格： | 5mg | 产品价格： | ￥880.0 |
| 规格： | 10mg | 产品价格： | ￥1680.0 |
| 产品编号 | bs-0437P |
| 英文名称 | Streptavidin |
| 中文名称 | 链霉亲和素 |
| 英文别名 | SA V1; SA V2; Streptavidin V1; Streptavidin V2; SA. |
| 中文别名 | 链亲和素; Streptavidin 链霉亲和素; |
| 性状 | Lyophilized |
| 纯化方法 | AC |
| 理论分子量 | 12 |
| 实际分子量 | 12/38/55 kDa |
| 储存液 | Lyophilized from 0.22um filtered solution in PBS (pH7.4). |
| 亚基 | Homotetramer (By similarity). |
| 亚细胞定位 | Secreted. |
| 相似性 | Belongs to the avidin/streptavidin family.
Contains 1 avidin-like domain. |
| 功能 | The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin). |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Streptavidin is a tetrameric protein composed of identic subunits. Each subunit binds one biotin molecule with a KD of ~1x10-15M. The preparation contains an N- and C-terminal shortened variant (core streptavidin) with improved properties concerning homogeneity, solubility, resistance towards proteolytic degradation and accessibility of the biotin binding pocket as compared to native streptavidin. The high affinity recognition of biotin and biotinylated molecules has made streptavidin one of the most important components in diagnostics and laboratory kits. |
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文献和实验[IF={{ 9 }}] {Wan Yangu. et al. C1GalT1 expression reciprocally controls tumour cell-cell and tumour-macrophage interactions mediated by galectin-3 and MGL with double impact on cancer development and progression. CELL DEATH DIS. 2023 Aug;14(8):1-15} {WB} {Human}
[IF={{ 8.5 }}] {Jingrui Yuan. et al. Hue-change coupled with CRISPR-Cas12a lateral flow assay for the semiquantitative detection of Salmo salar adulteration. FOOD CHEM. 2025 Jan;463:141088} {} {}
[IF={{ 8.2 }}] {Yiting Wang. et al. Enhanced detection of ligand-PPARγ binding based on surface plasmon resonance through complexation with SRC1- or NCOR2-related polypeptide. INT J BIOL MACROMOL. 2024 May;268:131865} {Other} {}
[IF={{ 8.008 }}] {Li Fu. et al. A General Route for Chemiluminescence of n-Type Au Nanocrystals. ANAL CHEM. 2022;94(24):8811–8817} {Other} {}
[IF={{ 8.008 }}] {Yi Ma. et al. Flap Endonuclease-Induced Steric Hindrance Change Enables the Construction of Multiplex and Versatile Lateral Flow Strips for DNA Detection. ANAL CHEM. 2022;94(42):14725–14733} {Other} {Other}
Colloidal Gold/Streptavidin Methods
. This nonspecific binding has been attributed both to its high isoelectric point (PI = 10) and to the fact that the protein is glycosylated (3 , 4 ). Because of the problem of nonspecific binding of avidin, streptavidin has largely replaced avidin
Smart Polymer-Streptavidin Conjugates
The conjugation of stimuli-responsive, or “smart,” polymers to streptavidin is described. The polymer is synthesized with a thiol-reactive end-group, which is used to end-graft the polymer to cysteine or lysine side-chains
Covalent Coupling of DNA Oligonucleotides and Streptavidin
Semisynthetic DNA-protein conjugates are synthesized by covalent coupling of thiol-modified DNA oligonucleotides and streptavidin. The resulting conjugates have a binding capacity for four equivalents of biotin and one nucleic acid
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