PCDHA8 Antibody Blocking Peptide(bs-11122P)-500ug

PCDHA8 Antibody Blocking Pepti

de(bs-11122P)-500ug
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  • ¥880
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  • bs-11122P
  • 2025年10月16日
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      500ug

    产品编号bs-11122P
    英文名称PCDHA8 Antibody Blocking Peptide
    中文名称原钙粘附蛋白α8封闭多肽
    英文别名KIAA0345 like 6; PCDH ALPHA8; Protocadherin alpha 8; PCDA8_HUMAN; PCDH alpha 8; PCDH-alpha-8; Protocadherin alpha 8; Protocadherin alpha-8.
    纯化方法HPLC
    亚细胞定位Cell membrane; Single-pass type I membrane protein
    相似性Contains 6 cadherin domains.
    功能PCDHA8 is most likely to play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. Two different isoforms are known.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHA8 (protocadherin alpha 8) is a 950 amino acid single-pass type I membrane protein that contains six cadherin domains and is encoded by a gene which is located within the protocadherin alpha gene cluster on human chromosome 5. Existing as multiple alternatively spliced isoforms, PCDHA8 functions as a potential calcium-dependent cell adhesion protein that may be involved in the establishment and maintenance of neuronal connections within the brain.

     

     

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