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- 2025年10月16日
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500ug
| 产品编号 | bs-11115P |
| 英文名称 | PCDHA1 Antibody Blocking Peptide |
| 中文名称 | 原钙粘附蛋白α1封闭多肽 |
| 英文别名 | KIAA0345 like 13; PCDH alpha1; PCDHA 1; Protocadherin alpha 1; PCDA1_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Cell Adhesion Proteins > Membrane Proteins Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Cadherins |
| 亚细胞定位 | Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. |
| 相似性 | Contains 6 cadherin domains. |
| 功能 | PCDHA1 (Protocadherin alpha 1) is a member of the protocadherin family, a subgroup of the cadherin superfamily. Protocadherins are neural cadherin-like cell adhesion proteins that are integral membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific neuronal connections in the brain. PCDHA1 is one of fifteen tandemly arranged genes within the alpha cluster of protocadherin genes on 5q31. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHA1 (protocadherin alpha 1), also known as PCDH-ALPHA1, is a 950 amino acid, single-pass type I membrane protein that contains six cadherin domains. Functioning as a potential calcium-dependent cell-adhesion protein, PCDHA1 has been suspected to play a role in the creation and maintenance of neuronal connections. Three isoforms of PCDHA1 exists due to alternative splicing events. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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