- ￥880
- Bioss
- bs-14337P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-14337P |
| 英文名称 | INTS7 Antibody Blocking Peptide |
| 中文名称 | 1号染色体开放阅读框73封闭多肽 |
| 英文别名 | INTS7; 5930412E23Rik; DKFZP434B168; C1orf73; Chromosome 1 open reading frame 73; chunp6916; DKFZp434B168; FLJ10736; FLJ12447; Int7; INT7_HUMAN; integrator complex subunit 7; INTS7; Ints7 integrator complex subunit 7; OTTHUMP00000035211; RGD1308014. |
| 纯化方法 | HPLC |
| 亚基 | Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, CPSF3L/INTS11 and INTS12. Interacts with NABP2. |
| 亚细胞定位 | Nucleus. Chromosome. Localizes to sites of DNA damage in a H2AX-independent manner. |
| 相似性 | Belongs to the Integrator subunit 7 family. |
| 功能 | Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Plays a role in DNA damage response (DDR) signaling during the S phase. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a subunit of the integrator complex. The integrator complex associates with the C-terminal domain of RNA polymerase II and mediates 3'-end processing of the small nuclear RNAs U1 and U2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010] |
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INTS7 Antibody Blocking Peptide(bs-14337P)-500ug
￥880
