PCDH18 Antibody Blocking Peptide(bs-11112P)-500ug

PCDH18 Antibody Blocking Pepti

de(bs-11112P)-500ug
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  • ¥880
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  • bs-11112P
  • 2025年10月16日
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      500ug

    产品编号bs-11112P
    英文名称PCDH18 Antibody Blocking Peptide
    中文名称原钙粘附蛋白18封闭多肽
    英文别名PCD18_HUMAN; PCDH18; PCDH68L; protocadherin 18; protocadherin 68-like protein; Protocadherin-18.
    纯化方法HPLC
    研究领域

    Neuroscience > Cell Adhesion Proteins > Membrane Proteins

    Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Cadherins

    亚细胞定位Cell membrane.
    组织特异性Expressed in all tissues, with highest expression in lung and ovary.
    相似性Contains 6 cadherin domains.
    功能Potential calcium-dependent cell-adhesion protein.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDH18 (protocadherin 18), also known as PCDH68L, is a 1,135 amino acid single-pass type I cell membrane protein that contains six cadherin domains and a cytoplasmic tail that differs from classical cadherins. Expressed ubiquitously with highest expression in ovary and lung, PCDH18 interacts with Dab1 and functions as a potential calcium-dependent adhesion protein that may be involved in the establishment of cell-cell connections in the brain. Multiple isoforms of PCDH18 exist due to alternative splicing events.

     

     

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