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500ug
| 产品编号 | bs-11111P |
| 英文名称 | PCDH1 Antibody Blocking Peptide |
| 中文名称 | 原钙粘附蛋白1封闭多肽 |
| 英文别名 | Cadherin like 1; Cadherin like protein 1; PC 42; PC42; PCDH 1; PCDH-1; PCDH 42; PCDH42; Protocadherin 1; Protocadherin 42; Protocadherin1; Protocadherin42. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Cell junction. Cell membrane. Single-pass type I membrane protein. Note=Found at cell-cell boundaries and probably at cell-matrix boundaries. |
| 组织特异性 | Highly expressed in the brain and neuro-glial cells. |
| 相似性 | Contains 7 cadherin domains. |
| 功能 | PCDH1 (Protocadherin 1) belongs to the protocadherin family, a subfamily of the cadherin superfamily. It is a membrane protein found at cell-cell boundaries suggesting a role in cell-cell interaction processes. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Protocadherins are a subfamily of cadherins, a large group of related glycoproteins that mediate calcium-dependent cell-to-cell adhesion via a homophilic mechanism. Involved in a variety of functions, protocadherins help to regulate neural development and synapse formation. PCDH1 is a 1,026 amino acid single-pass type I membrane protein that contains seven cadherin domains and is a member of the protocadherin family. Localized to cell-cell and cell-matrix boundaries and expressed at high levels in brain and neuro-glial cells, PCDH1 is thought to be involved in cell adhesion and cell-cell interactions and may play a role in neuronal development. PCDH1 contains a C-terminal cytoplasmic region, an extracellular region and a transmembrane region, and is expressed as two isoforms due to alternative splicing events. |
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PCDH1 Antibody Blocking Peptide(bs-11111P)-500ug
¥880







