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500ug
| 产品编号 | bs-11102P |
| 英文名称 | Neprilysin 2 Antibody Blocking Peptide |
| 中文名称 | 脑啡肽酶2封闭多肽 |
| 英文别名 | Neprilysin-like Protease beta; Mel transforming oncogene like 1; Membrane metallo endopeptidase like 1; Membrane metallo endopeptidase like 2; MMEL1; Neprilysin2; Neprilysin-2; Neprilysin Like 1; MMEL2; NEPII; NL1; NL2; SEP; Soluble secreted endopeptidase. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Proteolysis / Ubiquitin > Proteolytic enzymes > Other proteases Neuroscience > Cell Adhesion Proteins > Membrane Proteins |
| 亚细胞定位 | Membrane. Secreted. A secreted form produced by proteollytic cleavage also exists. |
| 组织特异性 | Predominantly expressed in testis. Weakly expressed in brain, kidney and heart. |
| 翻译后修饰 | N-glycosylated. |
| 相似性 | Belongs to the peptidase M13 family. |
| 功能 | Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificity with MME and cleaves peptides at the same amide bond. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart. [provided by RefSeq, Jul 2008] |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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