- ￥880
- Bioss
- bs-11092P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-11092P |
| 英文名称 | MDGA2 Antibody Blocking Peptide |
| 中文名称 | 神经元膜糖蛋白锚定蛋白2封闭多肽 |
| 英文别名 | MAM domain-containing glycosylphosphatidylinositol anchor protein 2; MAM domain-containing protein 1; MAMDC1; Mdga2; MDGA2_HUMAN; UNQ8188/PRO23197; c14_5286. |
| 纯化方法 | HPLC |
| 研究领域 | Developmental Biology > Organogenesis > Nervous system development Neuroscience > Cell Adhesion Proteins > Membrane Proteins |
| 亚细胞定位 | Cell membrane. |
| 相似性 | Contains 6 Ig-like (immunoglobulin-like) domains. Contains 1 MAM domain. |
| 功能 | May involved in cell-cell interactions. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | MDGA2 is a cell membrane protein which contains six Ig-like (immunoglobulin-like) domains and one MAM domain. Analyses of the full-length coding region of MDGA1 and MDGA2 indicate that they encode proteins that comprise a novel subgroup of the Ig superfamily and have a unique structural organization consisting of six immunoglobulin (Ig)-like domains followed by a single MAM domain. Biochemical characterization demonstrates that MDGA1 and MDGA2 proteins are highly glycosylated, and that MDGA1 is tethered to the cell membrane by a GPI anchor. The MDGAs are differentially expressed by subpopulations of neurons in both the central and peripheral nervous systems, including neurons of the basilar pons, inferior olive, cerebellum, cerebral cortex, olfactory bulb, spinal cord, and dorsal root and trigeminal ganglia. The similarity of MDGAs to other Ig-containing molecules and their temporal-spatial patterns of expression within restricted neuronal populations, for example migrating pontine neurons and D1 spinal interneurons, suggest a role for these novel proteins in regulating neuronal migration, as well as other aspects of neural development, including axon guidance. |
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MDGA2 Antibody Blocking Peptide(bs-11092P)-500ug
￥880
