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- Bioss
- bs-16503P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-16503P |
| 英文名称 | HHV8 ORF62 Antibody Blocking Peptide |
| 中文名称 | 人类疱疹病毒8 ORF62封闭多肽 |
| 英文别名 | HHV8; Human herpes virus 8; VP19_HHV8P; Kaposi's sarcoma associated herpesvirus; KSHV; ORF62; Triplex capsid protein 1; TRX1; |
| 纯化方法 | HPLC |
| 亚基 | Interacts with TRX2, MCP and capsid vertex component 2/CVC2. |
| 相似性 | Belongs to the herpesviridae TRX1 protein family. |
| 功能 | Structural component of the T=16 icosahedral capsid. The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes. These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi's sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman's disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. At least five major proteins are likely to be involved in the assembly of the HHV-8 capsid, including a protease (encoded by ORF17), the major capsid protein (encoded by ORF25), and three other smaller capsid proteins (encoded by ORF62, ORF26, and ORF65). Previous structural studies have shown that the HSV-1 triplex is a monomer of VP19c and a dimer of VP23 and that the HCMV triplex is similarly composed of a monomer and a dimer. By analogy, the KSHV triplexes are likely also composed of a monomer of the ORF62 protein and a dimer of the ORF26 protein, which are the respective homologs of VP19c and VP23. |
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HHV8 ORF62 Antibody Blocking Peptide(bs-16503P)-500ug
￥880
