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500ug
| 产品编号 | bs-16499P |
| 英文名称 | HEYL Antibody Blocking Peptide |
| 中文名称 | 转录因子HRT3封闭多肽 |
| 英文别名 | bHLHb33; Class B basic helix loop helix protein 33; Class B basic helix-loop-helix protein 33; Hairy enhancer of split related with YRPW motif like; Hairy related transcription factor 3; Hairy-related transcription factor 3; Hairy/enhancer of split related with YRPW motif 3; Hairy/enhancer of split related with YRPW motif like; Hairy/enhancer of split related with YRPW motif like protein; Hairy/enhancer-of-split related with YRPW motif-like protein; HEY like protein; HEY3; HEYL; HEYL protein; HEYL_HUMAN; hHeyL; hHRT3; HRT 3; HRT-3; HRT3; MGC12623. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Domain Families > HLH / Leucine Zipper > HLH Epigenetics and Nuclear Signaling > Transcription > Transcription Factors |
| 亚细胞定位 | Nucleus. |
| 相似性 | Belongs to the HEY family. Contains 1 basic helix-loop-helix (bHLH) domain. Contains 1 Orange domain. |
| 功能 | Downstream effector of Notch signaling which may be required for cardiovascular development (By similarity). Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3' (By similarity). Represses transcription by the cardiac transcriptional activators GATA4 and GATA6. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The sequence of the encoded protein contains a conserved bHLH and orange domain, but its YRPW motif has diverged from other HESR family members. It is thought to be an effector of Notch signaling and a regulator of cell fate decisions. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
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HEYL Antibody Blocking Peptide(bs-16499P)-500ug
¥880







