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| 规格: | 100ug | 产品价格: | ¥2280.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥6880.0 |
| 规格: | 20ug | 产品价格: | ¥680.0 |
| 产品编号 | bs-43082P |
| 英文名称 | Recombinant human TSH Alpha/Beta Heterodimer protein, C-His (HEK293) |
| 中文名称 | 重组人促甲状腺素蛋白 |
| 英文别名 | CHNG4; Thyroid stimulating hormone beta subunit; Thyroid stimulating hormone, beta precursor; Thyrotropin beta subunit; TSHB_HUMAN; Thyrotropin subunit beta; Thyroid-stimulating hormone subunit beta; TSH-B; TSH-beta; TSH beta; Thyrotropin beta chain; Thyrotropin alfa; Recombinant human TSH Alpha/Beta Heterodimer protein, C-His (HEK293) |
| 性状 | Lyophilized |
| 纯化方法 | AC |
| 研究领域 | Cancer > Cancer Metabolism > Metabolic signaling pathway > Hormone biosynthesis Metabolism > Pathways and Processes > Endocrine metabolism > Hormone biosynthesis Neuroscience > Endocrine system > Thyroid axis Signal Transduction > Growth Factors/Hormones > Hormones |
| 亚基 | Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin. |
| 亚细胞定位 | Secreted. |
| 相似性 | Belongs to the glycoprotein hormones subunit beta family. |
| 功能 | Indispensable for the control of thyroid structure and metabolism. |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013] |

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文献和实验Experimental Applications: Human Acetylcholinesterase as a Model Nervous System Protein
, 5 ng in vitro-transcribed AChE mRNA directed the production of catalytically active recombinant human acetylcholinesterase (rHAChE), at levels of approx 10-fold above background oocyte levels (Table 6 ). Oocyte-produced rHAChE was sensitive to the AChE
Preparation of Recombinant Protein Spotted Arrays for Proteome‐Wide Identification of Kinase Targets
functional biology and proteomics. Mol. Biochem. Parasitol. 118:155‐165. Bussow, K., Nordhoff, E., Lubbert, C., Lehrach, H., and Walter, G. 2000. A human cDNA library for high
Introduction of human 14-3-3 proteins
whose members have been shown to activate tyrosine and tryptophan hydroxylases,inhibit protein kinase C and possess phospholipase A2 activity in vitro.We have isolated and analyzed a 14-3-3 protein cDNA clone (H14-3-3)from a human fetal brain cDNA library
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