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- Bioss
- bs-11080P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-11080P |
| 英文名称 | MPZL2 Antibody Blocking Peptide |
| 中文名称 | 髓鞘蛋白P0样蛋白2封闭多肽 |
| 英文别名 | Epithelial V like antigen 1; epithelial V-like antigen; EVA; EVA1; MPZL2; MPZL2 myelin protein zero like 2; myelin protein zero-like 2; Myelin protein zero like protein 2; MPZL2_HUMAN. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Cell Membrane; Single-pass type I membrane protein, cytoskeleton |
| 组织特异性 | Expressed in thymocytes and thymic stromal cells; expression elevated in some T-cell leukemias. |
| 相似性 | Belongs to the myelin P0 protein family.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. |
| 功能 | Mediates homophilic cell-cell adhesion. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. This gene is expressed in the thymus and in several epithelial structures early in embryogenesis. It is highly homologous to the myelin protein zero and, in thymus-derived epithelial cell lines, is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain; a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]. |
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MPZL2 Antibody Blocking Peptide(bs-11080P)-500ug
￥880
