Bivalirudin Antibody Blocking Peptide(bs-4561P)-500ug

Bivalirudin Antibody Blocking

Peptide(bs-4561P)-500ug
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  • ¥880
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  • bs-4561P
  • 2025年10月16日
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      500ug

    产品编号bs-4561P
    英文名称Bivalirudin Antibody Blocking Peptide
    中文名称比伐卢定(水蛭素类似物)封闭多肽
    英文别名Bivalirudin; 128270-60-0
    中文别名Hirudin
    性状Lyophilized
    纯化方法HPLC
    理论分子量2.108
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Bivalirudin is a specific and reversible direct thrombin inhibitor (DTI). Chemically, it is a synthetic congener of the naturally occurring drug hirudin (found in the saliva of the medicinal leech Hirudo medicinalis). Bivalirudin is a DTI that overcomes many limitations seen with indirect thrombin inhibitors, such as heparin. Bivalirudin is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin. It inhibits both circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation. Bivalirudin has a quick onset of action and a short half-life. It does not bind to plasma proteins (other than thrombin) or to red blood cells. Therefore, it has a predictable antithrombotic response. There is no risk for Heparin Induced Thrombocytopenia/Heparin Induced Thrombosis-Thrombocytopenia Syndrome (HIT/HITTS). It does not require a binding cofactor such as antithrombin and does not activate platelets. These characteristics make bivalirudin an ideal alternative to heparin.

     

     

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