PTHLH Antibody Blocking Peptide(bs-1107P)-500ug

PTHLH Antibody Blocking Peptid

e(bs-1107P)-500ug
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  • ¥880
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  • bs-1107P
  • 2025年10月16日
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      500ug

    产品编号bs-1107P
    英文名称PTHLH Antibody Blocking Peptide
    中文名称甲状旁腺激素相关蛋白封闭多肽
    英文别名Parathyroid Hormone Related Protein; Parathyroid Hormone-related Protein; HHM; MGC14611; Osteostatin; Parathyroid hormon like hormone isoform 2 preproprotein; Parathyroid hormone like hormone; Parathyroid hormone like hormone isoform 1 preproprotein; Parathyroid hormone like protein; Parathyroid hormone like related protein; Parathyroid Hormone Receptor 1; Parathyroid like protein; PLP; PTH related protein; PTH rP; PTHrP; PTHR; PTHRP.
    纯化方法HPLC
    研究领域

    Cell Biology > Cell Cycle > Cell differentiation

    Signal Transduction > Growth Factors/Hormones > Hormones

    Stem Cells > Mesenchymal Stem Cells > Surface Molecules

    亚基PTHrP interacts with PTH1R (via N-terminal extracellular domain).
    亚细胞定位Cytoplasmic, Nuclear and Secreted
    组织特异性Expressed in most tissues. Most abundant in kidney, bone and liver.
    相似性Belongs to the G-protein coupled receptor 2 family.
    功能This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Parathyroid related protein (PTHLH), is a polypeptide hormone produced by almost every tissue of the body and is closely related to parathyroid hormone (PTH). It signals through its receptor, PTHR1, regulating endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. The receptor for this hormone (PTHRP) is responsible for most cases of humoral hypercalcemia of malignancy.

     

     

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