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500ug
| 产品编号 | bs-1107P |
| 英文名称 | PTHLH Antibody Blocking Peptide |
| 中文名称 | 甲状旁腺激素相关蛋白封闭多肽 |
| 英文别名 | Parathyroid Hormone Related Protein; Parathyroid Hormone-related Protein; HHM; MGC14611; Osteostatin; Parathyroid hormon like hormone isoform 2 preproprotein; Parathyroid hormone like hormone; Parathyroid hormone like hormone isoform 1 preproprotein; Parathyroid hormone like protein; Parathyroid hormone like related protein; Parathyroid Hormone Receptor 1; Parathyroid like protein; PLP; PTH related protein; PTH rP; PTHrP; PTHR; PTHRP. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Cell Cycle > Cell differentiation Signal Transduction > Growth Factors/Hormones > Hormones Stem Cells > Mesenchymal Stem Cells > Surface Molecules |
| 亚基 | PTHrP interacts with PTH1R (via N-terminal extracellular domain). |
| 亚细胞定位 | Cytoplasmic, Nuclear and Secreted |
| 组织特异性 | Expressed in most tissues. Most abundant in kidney, bone and liver. |
| 相似性 | Belongs to the G-protein coupled receptor 2 family. |
| 功能 | This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Parathyroid related protein (PTHLH), is a polypeptide hormone produced by almost every tissue of the body and is closely related to parathyroid hormone (PTH). It signals through its receptor, PTHR1, regulating endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. The receptor for this hormone (PTHRP) is responsible for most cases of humoral hypercalcemia of malignancy. |
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PTHLH Antibody Blocking Peptide(bs-1107P)-500ug
¥880







