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500ug
| 产品编号 | bs-17541P |
| 英文名称 | HLA DP Antibody Blocking Peptide |
| 中文名称 | 组织相容性抗原DP封闭多肽 |
| 英文别名 | DP(W3); DP(W4); HLA class II histocompatibility antigen DP alpha 1 chain; HLA class II histocompatibility antigen DP alpha chain; HLA DP1A; HLA DPA 1; HLA SB alpha chain; HLADP; HLADPA1; HLASB; HLASB histocompatibility type; Human MHC class II HLA SB alpha gene; Major histocompatibility complex class II DP alpha 1; MHC class II antigen; MHC class II DP3 alpha; MHC class II DPA1; MHC class II HLA DPA1 antigen; PLT1; Primed lymphocyte test 1. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Adaptive Immunity > MHC > Class II |
| 亚细胞定位 | Type I membrane protein. |
| 功能 | HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a vital role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells and macrophages). Within the DP molecule the alpha and beta chain contain the polymorphisms governing the peptide binding specificities, resulting in up to 4 different molecules. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008] |
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HLA DP Antibody Blocking Peptide(bs-17541P)-500ug
¥880








