- ￥880
- Bioss
- bs-17535P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-17535P |
| 英文名称 | OTOP2 Antibody Blocking Peptide |
| 中文名称 | OTOP2蛋白封闭多肽 |
| 英文别名 | Otop2; OTOP2_HUMAN; Otopetrin-2. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Sensory System > Auditory system |
| 亚细胞定位 | Membrane. |
| 相似性 | Belongs to the otopetrin family. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Otopetrins are multi-transmembrane domain proteins that share conserved gene and protein structure and are possibly involved in the formation of otoconia and otoliths. Located in the utricle and saccule of the inner ear, otoconia are complex calcium carbonate biominerals that are required for the normal sensation of gravity and linear acceleration. Vertigo and loss of balance may be attributed to degeneration of displacement of otoconia. The otopetrin family consists of three proteins, OTOP1, OTOP2 and OTOP3. These proteins have 12 putative transmembrane domains that are clustered into three otopetrin domains (OD-I, II and III). OTOP1 was the first described member of the Otopetrin family. Mutations of OTOP1 leads to absence of otoconia or otoliths, though inner ear development is normal. OTOP2 and OTOP3 share significant structural similarity with OTOP1 and may also play a role in the formation of mineralized structures. |
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OTOP2 Antibody Blocking Peptide(bs-17535P)-500ug
￥880
